Publications

Evaluating Real-World Outcome Alignment With Controlled Clinical Trial Results

Samstein, R.M., Lee, CH., Shoushtari, A.N. et al. Evaluating Real-World Outcome Alignment With Controlled Clinical Trial Results. Nat Genet 51, 202–206 (2019). https://doi.org/10.1038/s41588-018-0312-8

Integrating Biomarker Analysis Into Modern Clinical Trial Protocols

Aracena, K.A., Lin, YL., Luo, K. et al. Integrating Biomarker Analysis Into Modern Clinical Trial Protocols. Nat Genet 56, 408–419 (2024). https://doi.org/10.1038/s41588-024-01668-z

Patient Response Variability and Its Impact on Clinical Trial Outcomes

Ma, PF., Liu, YL., Guo, C. et al. Patient Response Variability and Its Impact on Clinical Trial Outcomes. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01683-0

Optimizing Clinical Trial Design Through Adaptive Methodologies and Real-Time Data Analysis

Yang, H., Wang, J., Didion, J. et al. Optimizing Clinical Trial Design Through Adaptive Methodologies and Real-Time Data Analysis. Nat Genet 43, 648–655 (2011). https://doi.org/10.1038/ng.847

Safety and Efficacy Evaluation of Investigational Therapeutics in Controlled Clinical Environments

Kunkle, B.W., Grenier-Boley, B., Sims, R. et al. Safety and Efficacy Evaluation of Investigational Therapeutics in Controlled Clinical Environments. Nat Genet 51, 414–430 (2019). https://doi.org/10.1038/s41588-019-0358-2